Automotive and Transportation
Source : (remove) : Daily
RSS • JSON • XML • CSV
Automotive and Transportation
Source : (remove) : Daily
RSS • JSON • XML • CSV

Zinc-transporting protein contributes to aggressive growth of brain tumor, OU researchers find


  Copy link into your clipboard //automotive-transportation.news-articles.net/co .. e-growth-of-brain-tumor-ou-researchers-find.html
  Print publication without navigation Published in Automotive and Transportation on by Daily
          🞛 This publication is a summary or evaluation of another publication 🞛 This publication contains editorial commentary or bias from the source

  In a study published Wednesday in the Proceedings of the National Academy of Sciences (PNAS), University of Oklahoma researchers detail their discoveries about why the brain tumor glioblastoma is...

Researchers at Osaka University have discovered that a zinc-transporting protein, ZIP4, plays a significant role in the aggressive growth of glioblastoma, a type of brain tumor. The study, published in the journal Oncogene, found that ZIP4 increases the uptake of zinc into glioblastoma cells, which in turn activates the mTOR signaling pathway, promoting rapid cell proliferation. The research also showed that higher levels of ZIP4 were associated with poorer prognosis in glioblastoma patients. By using siRNA to knock down ZIP4 expression, the researchers were able to inhibit tumor growth in experimental models, suggesting that targeting ZIP4 could be a potential therapeutic strategy for treating this aggressive cancer.

Read the Full Daily Article at:
[ https://medicaldialogues.in/oncology/news/zinc-transporting-protein-contributes-to-aggressive-growth-of-brain-tumor-ou-researchers-find-147778 ]

Publication Contributing Sources